GOOD tours steer clear of places where the World Health Organization recommends - or the Peruvian Government requires - vaccinations.
However, we do recommend that if you are heading for the Amazon, that you get prophylactic Malaria medication (and take it, too!) If you are planning on exploring deeper into the rainforest or other unusual places in earnest on your own, please get advice from a specialized hospital or medical center.
Peru visitors should also be aware that eating from street vendors is concidered safe only if the food is boiled or can be peeled! Tap water should not be drunk anywhere unless is has been boiled or treated with iodine. But bottled water is available throughout Peru.
Further to the general advice about altitude sickness: Note that, when you are walking at high altitude, the body needs sugar, which can be carried conveniently in the form of a block of crystallized pure cane sugar, called chancaca, and easily found in the markets.
For more information on immunizations for travel to Peru, see the website of the World Health Organization at: http://www.who.int